' 
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Moderately Good
Based on 4 Reviews
7.7
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Folate (400 mcg as (6S)-5-MTHF [(6S)-5-Methyltetrahydrofolate Glucosamine Salt)
680 mcg DFE‡
170%
Top Medical Research Studies
7
Folate linked to reduced knee pain
Associations between folate intake and knee pain, inflammation mediators and comorbid conditions in patients with symptomatic knee osteoarthritis.
Directly addresses folate's impact
We explored the relationship between folate intake and knee pain in patients suffering from knee osteoarthritis (OA) over a two-year period. In this insightful study, data was collected from participants enrolled in a rigorous clinical trial designed to assess the effects of vitamin D supplementation. While the original trial focused on vitamin D, our post-hoc analysis allowed us to dive into the potential benefits of folate on knee pain and related conditions.
Through the use of dietary questionnaires, we assessed the average daily folate consumption of participants. In addition to evaluating knee pain levels at various intervals, other factors such as inflammatory markers, muscle strength, and comorbidities were also monitored. Impressively, we found that increased folate intake was associated with reduced knee pain and lower levels of inflammatory substances known as adipokines.
Furthermore, individuals with higher folate consumption reported fewer comorbid conditions, suggesting that folate may indeed play a role in enhancing overall health for those dealing with knee OA. However, while our findings are promising, they highlight the need for further research to fully understand the extent of folate's impact in this context.
Through the use of dietary questionnaires, we assessed the average daily folate consumption of participants. In addition to evaluating knee pain levels at various intervals, other factors such as inflammatory markers, muscle strength, and comorbidities were also monitored. Impressively, we found that increased folate intake was associated with reduced knee pain and lower levels of inflammatory substances known as adipokines.
Furthermore, individuals with higher folate consumption reported fewer comorbid conditions, suggesting that folate may indeed play a role in enhancing overall health for those dealing with knee OA. However, while our findings are promising, they highlight the need for further research to fully understand the extent of folate's impact in this context.
Read More
Most Useful Reviews
5.8
Natural formulation
This product contains a natural formulation of folic acid and does not cause stomach discomfort, making it a good option for my needs, particularly regarding my knee pain.
Read More
8.3
Easy to swallow
I'm using it for my knee pain. The capsules are small, tasteless, and easy to swallow. I opted for this brand due to its minimal ingredients and vegan formulation. It seems to be of good quality.
Read More
7.5
Reduced cramps
I didn't feel any noticeable changes. I'm taking this in the hope of increasing my blood count. However, my menstrual cramps have remarkably improved after using it; what was once excruciating pain is now just a sensation without the pain.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
- All Researches
7
Folate linked to reduced knee pain
Associations between folate intake and knee pain, inflammation mediators and comorbid conditions in patients with symptomatic knee osteoarthritis.
Directly addresses folate's impact
We explored the relationship between folate intake and knee pain in patients suffering from knee osteoarthritis (OA) over a two-year period. In this insightful study, data was collected from participants enrolled in a rigorous clinical trial designed to assess the effects of vitamin D supplementation. While the original trial focused on vitamin D, our post-hoc analysis allowed us to dive into the potential benefits of folate on knee pain and related conditions.
Through the use of dietary questionnaires, we assessed the average daily folate consumption of participants. In addition to evaluating knee pain levels at various intervals, other factors such as inflammatory markers, muscle strength, and comorbidities were also monitored. Impressively, we found that increased folate intake was associated with reduced knee pain and lower levels of inflammatory substances known as adipokines.
Furthermore, individuals with higher folate consumption reported fewer comorbid conditions, suggesting that folate may indeed play a role in enhancing overall health for those dealing with knee OA. However, while our findings are promising, they highlight the need for further research to fully understand the extent of folate's impact in this context.
Through the use of dietary questionnaires, we assessed the average daily folate consumption of participants. In addition to evaluating knee pain levels at various intervals, other factors such as inflammatory markers, muscle strength, and comorbidities were also monitored. Impressively, we found that increased folate intake was associated with reduced knee pain and lower levels of inflammatory substances known as adipokines.
Furthermore, individuals with higher folate consumption reported fewer comorbid conditions, suggesting that folate may indeed play a role in enhancing overall health for those dealing with knee OA. However, while our findings are promising, they highlight the need for further research to fully understand the extent of folate's impact in this context.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 4 Reviews
7.7
- All Reviews
- Positive Reviews
- Negative Reviews
5.8
Natural formulation
This product contains a natural formulation of folic acid and does not cause stomach discomfort, making it a good option for my needs, particularly regarding my knee pain.
8.3
Easy to swallow
I'm using it for my knee pain. The capsules are small, tasteless, and easy to swallow. I opted for this brand due to its minimal ingredients and vegan formulation. It seems to be of good quality.
7.5
Reduced cramps
I didn't feel any noticeable changes. I'm taking this in the hope of increasing my blood count. However, my menstrual cramps have remarkably improved after using it; what was once excruciating pain is now just a sensation without the pain.
1.3
Quality issues
Unfortunately, I experienced severe stomach pain after using it. While the quality seems good, it did not suit me, especially in relation to my knee pain.
